Carbamazepine 10,11-epoxide ( —— )

Catalog No. M28116 CAS No. 36507-30-9

Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	58	In Stock
25MG	115	In Stock
50MG	173	In Stock
100MG	258	In Stock
200MG	388	In Stock
500MG	642	In Stock
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Biological Information

Product Name

Carbamazepine 10,11-epoxide
Note

Research use only, not for human use.
Brief Description

Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.
Description

Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively.Carbamazepine 10,11-epoxide has anticonvulsant activity against maximal electroshock-induced seizures in mice.2It has been found in wastewater effluent.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PDE4;PDE4B1;PDE4D7
Research Area

——
Indication

——

Chemical Information

CAS Number

36507-30-9
Formula Weight

252.3
Molecular Formula

C15H12N2O2
Purity

>98% (HPLC)
Solubility

——
SMILES

NC(=O)N1c2ccccc2C2OC2c2ccccc12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Zheng-Qiang Zou, et al. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF- κ B Inhibition. J Pharmacol Exp Ther. 2017 Jul;362(1):67-77.

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